Health
Metformin as an Anti-Aging Drug: The Claims Versus the Trial Data
Biohackers take metformin to slow aging, but the trial designed to actually prove that, TAME, still has not finished enrolling.
May 6, 2024
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60 stories for“ageing”
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Health
Something Has Been Crossing Into the Ageing Human Brain That Was Not Supposed to Get In
Stanford researchers borrowed the trick a consumer ancestry test uses and found immune cells migrating out of the blood and into the human brain from middle age onwards. Mice do not do it. Nor did the primates tested alongside them.
Aug 25, 2026
Health
Retatrutide: The Triple Agonist Still Proving Itself
Retatrutide just posted phase 3 weight loss data hitting three hormone receptors at once. Here is what is confirmed and what remains unproven.
May 27, 2026
Health
Mounjaro and Zepbound: The Case for Two Hormones at Once
Tirzepatide just beat semaglutide head to head in a major trial. Here is what SURMOUNT and SURPASS data actually shows about hitting two receptors.
Dec 9, 2024
Health
Surviving a Gulf August: What Actually Works Against Extreme Heat
Heat illness is one of the most preventable medical emergencies there is, and most of the popular advice about it is either useless or actively wrong. The humidity is what changes the arithmetic.
Aug 8, 2026
Health
What GLP-1 Drugs Actually Do Inside Your Body
GLP-1 receptor agonists did not start as weight loss drugs. Here is the biology behind Ozempic, Mounjaro and the hormone they mimic.
Jan 25, 2024
Health
The Leading Cause of Blindness in Working-Age Adults Has No Symptoms Until It Is Nearly Too Late
Diabetic retinopathy does not hurt, does not blur vision early, and gives no warning a person can feel. By the time sight changes, the damage that caused it has usually been accumulating for years.
Jul 19, 2026
Health
Retatrutide's Third Receptor Is the Hormone That Raises Blood Sugar. Adding It On Purpose Is the Whole Idea
Semaglutide hits one receptor and tirzepatide hits two. The third one retatrutide adds is glucagon, which does the opposite of what a diabetes drug is supposed to do. It is also where the liver results and the safety questions both come from.
Aug 20, 2026
Health
Retatrutide's Phase 3 Run Is Nearly Complete. The Numbers Are the Largest Yet
TRIUMPH-2 and TRIUMPH-3 read out in July, following TRIUMPH-1 in May. Across the programme the triple agonist has produced weight loss in a range no approved obesity drug has reached, with a filing due in early 2027.
Aug 11, 2026
Health
The WHO Has Put Fungal Infections on the Danger List
New guidance targets a threat the agency calls one of the most neglected in global health. The problem is not just the infections, it is how few drugs exist to treat them.
Aug 4, 2026
