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55 stories for“maximalism”
VO2 max strongly predicts longevity, but the evidence that slow, low-intensity Zone 2 training is the best way to raise it is weaker than the trend suggests.
Jan 15, 2025
Mantra recitation across several religious traditions converges on a slow, sustained, vocalised exhalation. That is also the single breathing pattern with the best evidence for shifting the autonomic nervous system.
Sep 4, 2026
Fear, disrupted sleep, grief and irritability are common during conflict. Evidence-based support begins with safety and practical care, while recognizing when professional help is urgent.
Jul 25, 2026
Ozempic, Mounjaro and the drug that has not arrived yet are not three versions of the same thing. They hit different receptors, produce different results, and suit different people.
Aug 11, 2026
TRIUMPH-2 and TRIUMPH-3 read out in July, following TRIUMPH-1 in May. Across the programme the triple agonist has produced weight loss in a range no approved obesity drug has reached, with a filing due in early 2027.
Aug 11, 2026
Yogic breathing is unusual among wellness practices in having a measurable, replicated physiological effect. The size of it is modest, the mechanism is well understood, and a few of the more dramatic techniques carry real risk.
Sep 4, 2026
A delayed mortality count reveals the June heatwave’s true scale, showing why the deadliest climate disaster can pass quietly behind ordinary causes of death.
Jul 23, 2026
An engineered gum reduced HPV and nearly eliminated two bacteria linked to head and neck cancer. It is early work, and the delivery method is the genuinely clever part.
Aug 6, 2026
Semaglutide hits one receptor and tirzepatide hits two. The third one retatrutide adds is glucagon, which does the opposite of what a diabetes drug is supposed to do. It is also where the liver results and the safety questions both come from.
Aug 20, 2026
