GLP-1 Drugs Are Becoming More Than Weight Loss Medicine
Tirzepatide just earned an approval that has nothing to do with the scale. Here is what SELECT, FLOW and the new sleep apnea data show.
Jan 8, 2025

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41 stories for“cardiovascular disease”
Tirzepatide just earned an approval that has nothing to do with the scale. Here is what SELECT, FLOW and the new sleep apnea data show.
Jan 8, 2025

Semaglutide now has a heart disease approval too. Here is what the STEP and SELECT trial data really says, and what it does not.
Mar 13, 2024

SGLT2 inhibitors were developed to lower blood sugar by making you urinate it out. The glucose effect turned out to be the least interesting thing about them, and the kidney trials changed how this complication is treated.
Jul 25, 2026

FDA approval of the first oral PCSK9 inhibitor adds a once-daily option for adults who need greater LDL reduction, but it does not replace individualized cardiovascular care.
Aug 1, 2026

Retatrutide just posted phase 3 weight loss data hitting three hormone receptors at once. Here is what is confirmed and what remains unproven.
May 27, 2026

Men who used a sauna four to seven times a week had far fewer sudden cardiac deaths over twenty years than men who went once. That finding launched an industry. What the study can and cannot support, and who should be careful.
Sep 6, 2026

In a placebo controlled trial of 109 people, 58 per cent of the antibiotic group and 57.7 per cent of the supplement group reached the clinical target. The placebo group reached 23.1 per cent, and that third number is what makes the first two mean anything.
Aug 31, 2026

New mortality data pinpoints how much weekly strength training lowers death risk, and shows more is not always better.
Apr 10, 2025

Semaglutide hits one receptor and tirzepatide hits two. The third one retatrutide adds is glucagon, which does the opposite of what a diabetes drug is supposed to do. It is also where the liver results and the safety questions both come from.
Aug 20, 2026

Tirzepatide just beat semaglutide head to head in a major trial. Here is what SURMOUNT and SURPASS data actually shows about hitting two receptors.
Dec 9, 2024

Eleven thousand people wore a light sensor for a week. Three years later, those who slept in more than three lux, a very dim room, had thicker left ventricles and muscle that flexed less. The differences are small. Cardiologists still care.
Sep 12, 2026

Ozempic, Mounjaro and the drug that has not arrived yet are not three versions of the same thing. They hit different receptors, produce different results, and suit different people.
Aug 11, 2026

TRIUMPH-2 and TRIUMPH-3 read out in July, following TRIUMPH-1 in May. Across the programme the triple agonist has produced weight loss in a range no approved obesity drug has reached, with a filing due in early 2027.
Aug 11, 2026

Contracting muscle opens a separate doorway for glucose that does not require insulin at all. It explains why a ten minute walk after dinner works, why lifting weights matters more than it is given credit for, and why a hard sprint can send the number up.
Aug 9, 2026

Biohackers take metformin to slow aging, but the trial designed to actually prove that, TAME, still has not finished enrolling.
May 6, 2024

A UAE medical report found a natural death from sudden cardiac arrest. Egypt then exhumed the body for a second examination. Both of those facts are true, and neither cancels the other.
May 17, 2026

Two large pooled analyses now agree: the drop in mortality with more walking is steep up to about seven thousand steps a day and shallow after that. What the studies found, what they could not show, and what to do with a phone that counts.
Sep 6, 2026

A delayed mortality count reveals the June heatwave’s true scale, showing why the deadliest climate disaster can pass quietly behind ordinary causes of death.
Jul 23, 2026

Lilly does not expect to file for approval until the first quarter of 2027. Search the drug's name today and you can have a vial by the weekend. The gap between those two facts is where the harm happens.
Aug 20, 2026
