Metformin as an Anti-Aging Drug: The Claims Versus the Trial Data
Biohackers take metformin to slow aging, but the trial designed to actually prove that, TAME, still has not finished enrolling.
May 6, 2024

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31 stories for“controlled drugs”
Biohackers take metformin to slow aging, but the trial designed to actually prove that, TAME, still has not finished enrolling.
May 6, 2024

SGLT2 inhibitors were developed to lower blood sugar by making you urinate it out. The glucose effect turned out to be the least interesting thing about them, and the kidney trials changed how this complication is treated.
Jul 25, 2026

Ozempic, Wegovy and Mounjaro are all prescribable in the UAE, but shortages and insurance gaps shape who can actually get them.
Mar 10, 2025

Trial data on stopping semaglutide shows most of the lost weight comes back within a year. Here is what the STEP 1 extension found.
May 15, 2024

A phase 1 trial at the Charite in Berlin used CD19 CAR T cells, a treatment built for blood cancers, on patients who had already failed between five and eight biologic drugs. Disease activity fell in every one of them. Three reached medication free remission.
Aug 30, 2026

GLP-1 receptor agonists did not start as weight loss drugs. Here is the biology behind Ozempic, Mounjaro and the hormone they mimic.
Jan 25, 2024

Lilly does not expect to file for approval until the first quarter of 2027. Search the drug's name today and you can have a vial by the weekend. The gap between those two facts is where the harm happens.
Aug 20, 2026

Berberine lowers cholesterol and blood sugar in small trials, but comparing it to semaglutide misreads both the data and the biology.
Feb 14, 2024

Retatrutide just posted phase 3 weight loss data hitting three hormone receptors at once. Here is what is confirmed and what remains unproven.
May 27, 2026

Tirzepatide just beat semaglutide head to head in a major trial. Here is what SURMOUNT and SURPASS data actually shows about hitting two receptors.
Dec 9, 2024

The IDF and Diabetes and Ramadan International Alliance stratify patients into low, moderate and high risk, and updated the calculator for 2026. The assessment is meant to happen six to eight weeks ahead, which is when almost nobody books it.
Aug 3, 2026

The agency has issued no recommendation on a newly approved mRNA flu vaccine for older adults, citing legal uncertainty after a court froze Kennedy's overhauled vaccine advisory panel, leaving doctors' groups to fill the gap on their own.
Sep 27, 2026

Meta-analyses now put exercise's effect on depression in the same range as antidepressant trials, with real implications for regions like the Gulf.
Apr 14, 2026

Continuous monitoring is now recommended for adults with type 2 diabetes who are not on insulin at all, and the prerequisites for starting automated insulin delivery have been deleted rather than relaxed. Both changes are about access.
Aug 15, 2026

Oxford Population Health researchers found 37 per cent of adults enrolled in Our Future Health had hypertension, and 59 per cent of those, about 1.3 million people, were undiagnosed. Even diagnosed patients often had it poorly controlled.
Sep 25, 2026

Type 1 and type 2 are the two everyone knows. LADA is regularly mistaken for type 2 in adults, and MODY is a single-gene condition that can sometimes be treated with a tablet instead of insulin. The label decides the therapy.
Jul 7, 2026

One patient cannot bear a bedsheet touching their feet. Another cannot feel a nail through their shoe. Both have diabetic neuropathy, and the second is in more danger than the first.
Jul 28, 2026

Contracting muscle opens a separate doorway for glucose that does not require insulin at all. It explains why a ten minute walk after dinner works, why lifting weights matters more than it is given credit for, and why a hard sprint can send the number up.
Aug 9, 2026

In a placebo controlled trial of 109 people, 58 per cent of the antibiotic group and 57.7 per cent of the supplement group reached the clinical target. The placebo group reached 23.1 per cent, and that third number is what makes the first two mean anything.
Aug 31, 2026

The CDC's 1 October update counts 76 illnesses from E. coli, Salmonella or both, all traced to one lot of alfalfa seed. Six people have been hospitalised and none has died.
Oct 2, 2026

Three randomised trials put time-restricted eating against ordinary calorie control or against nothing. The eating window on its own did little. Combined with eating less, it did what eating less does. What that means for anyone considering it.
Sep 6, 2026

A randomised crossover trial with a sham unit found the effect only in participants aged 40 and over. It is also a secondary outcome analysis, it ran for a month, and it had fewer than ten people over 60 in it.
Aug 31, 2026

Trials now show insufficient sleep impairs insulin sensitivity directly, independent of weight gain, reshaping how doctors talk about diabetes risk.
Nov 2, 2024

Peptide is a chemical category, not a claim. The two versions most people actually buy are the ones with the least regulation and, oddly, the best safety record. Here is what the trials support and what physics gets in the way of.
Aug 20, 2026

A tiny implant paired with camera glasses can return useful central vision to some people with advanced macular degeneration, and Europe has cleared its sale.
Jul 23, 2026
