Health
Creatine: The Most-Studied Supplement and What It Actually Does
Decades of trials back creatine for muscle and strength, and newer research is testing brain benefits, but the hype has outrun some of the data.
Aug 19, 2024
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41 stories for“clinical trials”
Health
Berberine and the 'Nature's Ozempic' Claim: What Evidence Shows
Berberine lowers cholesterol and blood sugar in small trials, but comparing it to semaglutide misreads both the data and the biology.
Feb 14, 2024
Health
Six People With Rheumatoid Arthritis Were Given a Cancer Therapy and Three Have Been Off All Medication Since
A phase 1 trial at the Charite in Berlin used CD19 CAR T cells, a treatment built for blood cancers, on patients who had already failed between five and eight biologic drugs. Disease activity fell in every one of them. Three reached medication free remission.
Aug 30, 2026
Nutrition
Intermittent Fasting: What the Trials Actually Show
A major Cochrane review of nearly 2,000 people found intermittent fasting barely beats ordinary dieting. Here is what the data really supports.
Mar 10, 2026
Health
Vitamin D Supplements: A Reality Check on Who Actually Benefits
Large trials with more than 30,000 participants found vitamin D pills do little for people who are not deficient, reshaping decades of assumptions.
Jan 20, 2026
Health
Nearly Half the People in a Trial Put Their Type 2 Diabetes Into Remission. The Follow-Up Is the Interesting Part
DiRECT reported 46 per cent remission at one year and 36 per cent at two. Among those who lost more than ten kilograms, three quarters were in remission. At five years, the picture is more sobering and more useful.
Aug 12, 2026
Health
Exercise as Treatment: What Trials Show for Depression and Anxiety
Meta-analyses now put exercise's effect on depression in the same range as antidepressant trials, with real implications for regions like the Gulf.
Apr 14, 2026
Health
Mounjaro and Zepbound: The Case for Two Hormones at Once
Tirzepatide just beat semaglutide head to head in a major trial. Here is what SURMOUNT and SURPASS data actually shows about hitting two receptors.
Dec 9, 2024
Health
What Actually Happens When You Stop Taking a GLP-1
Trial data on stopping semaglutide shows most of the lost weight comes back within a year. Here is what the STEP 1 extension found.
May 15, 2024
Health
Retatrutide: The Triple Agonist Still Proving Itself
Retatrutide just posted phase 3 weight loss data hitting three hormone receptors at once. Here is what is confirmed and what remains unproven.
May 27, 2026
Health
PRIMA’s Retinal Implant Wins Approval to Restore Vision
A tiny implant paired with camera glasses can return useful central vision to some people with advanced macular degeneration, and Europe has cleared its sale.
Jul 23, 2026
Health
A Personalized Gene Therapy Helped Two Boys With Severe Epilepsy
Two individualized antisense treatments reduced the effects of a rare SCN2A disorder. The results are hopeful, but they come from two carefully monitored patients, not a broad trial.
Aug 1, 2026
Health
GLP-1 Drugs Are Becoming More Than Weight Loss Medicine
Tirzepatide just earned an approval that has nothing to do with the scale. Here is what SELECT, FLOW and the new sleep apnea data show.
Jan 8, 2025
Health
Ozempic and Wegovy: What the Trials Actually Showed
Semaglutide now has a heart disease approval too. Here is what the STEP and SELECT trial data really says, and what it does not.
Mar 13, 2024
Health
Metformin as an Anti-Aging Drug: The Claims Versus the Trial Data
Biohackers take metformin to slow aging, but the trial designed to actually prove that, TAME, still has not finished enrolling.
May 6, 2024
Nutrition
Ultra-Processed Food: What the Research Actually Shows
One rigorous NIH trial proved ultra-processed diets cause overeating. A UK parliamentary report says the classification behind it is too blunt.
Jun 2, 2026
Health
Retatrutide's Phase 3 Run Is Nearly Complete. The Numbers Are the Largest Yet
TRIUMPH-2 and TRIUMPH-3 read out in July, following TRIUMPH-1 in May. Across the programme the triple agonist has produced weight loss in a range no approved obesity drug has reached, with a filing due in early 2027.
Aug 11, 2026
Health
A Chewing Gum That Cut Oral HPV by up to 93 Percent
An engineered gum reduced HPV and nearly eliminated two bacteria linked to head and neck cancer. It is early work, and the delivery method is the genuinely clever part.
Aug 6, 2026
Health
GLP-1 Side Effects and Who Should Not Take Them
Nausea is the least of it. Here is an honest look at GLP-1 side effects, the thyroid warning, pancreatitis and who is advised to avoid them.
Jul 10, 2024
Health
Retatrutide Is Not Approved in Any Country. It Is Also for Sale in Most of Them
Lilly does not expect to file for approval until the first quarter of 2027. Search the drug's name today and you can have a vial by the weekend. The gap between those two facts is where the harm happens.
Aug 20, 2026
Health
Congo Has Started Vaccinating Against Ebola With a Vaccine Built for a Different Ebola
The only licensed Ebola vaccine was made for Zaire ebolavirus. The outbreak killing people in eastern Congo is Bundibugyo. Vaccination began this week anyway, with 20,000 of the 70,000 doses formally designated as a trial.
Aug 29, 2026
Health
What a Peptide Actually Is, and Why the Word Now Sells Almost Anything
Insulin is a peptide. So is Ozempic. So is the unlabelled vial someone is selling on Telegram. The word describes a chemical class, not a level of evidence, and that gap is where the market lives.
Aug 11, 2026
Health
Women Were Warned for Twenty Years That Hormone Therapy Raised Dementia Risk. A Study of 21,000 Points the Other Way.
Estrogen-only therapy was associated with 39 per cent lower odds of dementia, and with fewer amyloid plaques and tau tangles in donated brains. It is observational, and the group that receives it is unusual.
Aug 22, 2026
Nutrition
Salt and Blood Pressure: The Evidence, and the Gulf's Convenience-Food Problem
WHO sets a 5 gram salt ceiling; the Gulf's average intake runs far above it, driven largely by bread and processed food.
Jan 16, 2025
Nutrition
The Carnivore Diet's Evidence Problem, Explained Plainly
All meat, no plants, and a wave of enthusiastic testimonials online. The actual research base behind the claims is nine small studies with no control group at all.
Apr 5, 2026
Health
Continuous Glucose Monitors Without Diabetes: Useful Data or Noise?
Over-the-counter glucose monitors reached healthy consumers in 2024, but research suggests their readings may not mean what wearers assume.
Jul 22, 2025
Health
Strength Training for Longevity: Muscle as an Organ of Healthspan
New mortality data pinpoints how much weekly strength training lowers death risk, and shows more is not always better.
Apr 10, 2025
Health
An FDA Panel Just Backed Compounded BPC-157. That Is Not the Same as Approval
On 23 and 24 July, an FDA advisory committee looked at seven peptides and recommended that pharmacies be allowed to compound several of them. The vote is not binding, and the evidence gap has not moved.
Aug 11, 2026
Nutrition
Meal Timing and Late-Night Eating: What Circadian Nutrition Research Actually Shows
Chrononutrition research links late eating to worse metabolic outcomes, but the field is younger and messier than headlines suggest.
Sep 25, 2025
Nutrition
Why Fast Weight Loss Is Not Evidence That a Diet Is Right
Every restrictive plan produces results in the first month, including plans that contradict each other completely. That is a fact about restriction, not about the theory attached to it.
Jun 30, 2026
Health
Muscle Loss on GLP-1s: What the Evidence Really Shows
New body composition data compares lean mass loss on tirzepatide and semaglutide. Here is what is measured, and what remains unclear.
Jun 15, 2026
Nutrition
The Diabetic Diet Got a Rewrite: What Guidance Says Now
No more banned-food lists. Current diabetes nutrition guidance leans on carbohydrate quality and a simple divided plate, not counting or deprivation lists.
Sep 20, 2024
Nutrition
Histamine Intolerance: Popular Online, Thin on Evidence
It has become one of the most searched explanations for unexplained symptoms. The mechanism is plausible, the tests being sold are not validated, and the diet is more restrictive than almost any other.
Aug 7, 2026
Health
Two Camps, One Diet: Why the Argument Never Converged
Doctors and followers spent a year disagreeing about nizam al-tayyibat without ever contradicting each other, because they were not answering the same question.
Jul 24, 2026
Nutrition
Coeliac, Wheat Allergy or Gluten Sensitivity: They Are Not the Same Thing
Three different conditions get flattened into one phrase. One is autoimmune, one is an allergy and one is a diagnosis of exclusion, and the testing order matters more than most people realise.
Aug 8, 2026
Health
How to Hold Yourself Together When the Region Is on Fire
One in five people who live through conflict develops a mental health condition. Most of the useful advice is unglamorous: fix sleep, ration news, keep routine, and treat connection as a necessity rather than a nicety.
Aug 13, 2026
Nutrition
Eating the Same Meal in a Different Order Cut Post-Meal Glucose by More Than a Third
Identical food, identical calories, identical macronutrients. The only variable was what went in the mouth first, and glucose at sixty minutes fell by 36.7 per cent. It is the cheapest intervention in diabetes nutrition.
Aug 18, 2026
Nutrition
The Low FODMAP Diet Is a Diagnostic Tool, Not a Way of Eating
It has strong evidence behind it for irritable bowel syndrome, and it is routinely misused. The elimination phase is meant to last weeks, and the part people skip is the part that matters.
Aug 7, 2026
Latest Trends
Digital detox is real now: dumbphones, offline clubs, and why
The smartphone backlash isn't niche anymore. Dumbphones are making a comeback, and people are seriously considering it. Here's the data.
Dec 10, 2024
Health
Zone 2 Cardio Versus VO2 Max: Sorting the Training Trend From the Evidence
VO2 max strongly predicts longevity, but the evidence that slow, low-intensity Zone 2 training is the best way to raise it is weaker than the trend suggests.
Jan 15, 2025
Nutrition
Plant Protein Versus Animal Protein: What Actually Matters in a Real Diet
Completeness and absorption differ between plant and animal protein, but for most people the practical gap is smaller than assumed.
Mar 12, 2026
